Research That Matters

Today, as little as 2 percent of the U.S. population is currently a part of clinical trials. Only a fraction of that includes individuals from the African American community, which makes up 12.1% and therefore the third largest group in the US.

Get Involved In Our Causes

What We Know About Gut Health

80%

of our immune cells exist in the gut, and unlike our genes, which is mostly fixed from birth, the microbiome can be changed by diet and overall lifestyle and microbial medicines. A healthy microbiome helps cancer drugs like checkpoint inhibitors to recognize, attack, and kill cancer cells better.

70%

of cancer patients don’t respond to this drug treatment due to severely damaged microbiomes which have limited kinds of bacteria. To this end, Stephanie Culler and her team at Persephone Biome are creating microbiome therapeutics that can help all cancer patients.

DESIGNING MICROBIOME THERAPEUTICS TO HELP CURE CANCER

STEPHANIE CULLER | TEDXSANDIEGOSALON

To this end, Stephanie Culler and her team at Persephone Biome are creating microbiome therapeutics that can help all cancer patients, but most importantly to convert non-responders into responders. Stephanie Culler, Ph.D. is co-founder and CEO of Persephone Biome, which is taking a unique approach to gut microbiome health, understanding and leveraging the rich metabolic capabilities of the microbes themselves to develop targeted nutritional products and better therapeutic drugs.

Stephanie was previously a senior scientist at Genomatica, developing and applying synthetic biology tools toward the engineering of micro-organisms as biocatalysts for the industrial production of sustainable chemicals. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

“All disease begins in the gut” – It's a quote attributed to the Ancient Greek physician Hippocrates nearly 2500 years ago.

Hippocrates, an ancient Greek physician who was quoted nearly 2500 years ago

something here

More About Us

Acclinate, a biotech company that improves health equity through clinical research, is proud to announce its partnership with Persephone Biosciences, a biotech company that uses artificial intelligence to develop microbial based immunotherapies, in its ARGONAUT study.

The observational study plans to enroll up to 4,000 advanced-stage non-small cell lung cancer (NSCLC), triple negative breast cancer (TNBC), colorectal cancer (CRC), and pancreatic cancer patients, which are four of the most common cancers. The enrollment will make it the largest clinical study to map gut microbiome cancer in the U.S.

Here’s the truth...

When it comes to medical research, we aren’t all included – not the way we should be, and not the way we can be.

People of Color make up 40 percent of the U.S. population, but there’s a real lack of diversity when it comes to people participating in genetic testing and clinical trials. That’s why certain medications don’t work for Black people, Hispanics and other People of Color, and that’s only scratching the surface. Let me put it this way: we’re underrepresented, which has only widened the number of healthcare disparities for us. That’s a problem, so let’s fix it.

Taking control of your healthcare is powerful, so I challenge you to raise your hand. When you participate in clinical or genetic research, you make a move toward changing the future of health for People of Color. By participating, you demand that you, your friends, your family, and future generations are represented. It’s long overdue – but together, progress can happen NOW.

Being #NOWINCLUDED means standing up for your health. Let’s participate, then celebrate.

Join The Community

Get Involved Where It Matters

We can all take charge of this amazing gatekeeper of our immune system and use it to prevent and fight disease.

Get Involved

We can all be active participants when it comes to gut Health.

Learn More About Our Causes

Your own genome is mostly fixed from the moment you are born. Discover how microbiomes can be modified by our overall lifestyle and microbial therapeutics.

Get Involved

The Microbiome Interaction in Cancer Patients

"Collect data for the development of the precision microbiome medicines and for the identification of companion diagnostics to guide therapeutic decisions."

Data collected from this study will be used to develop the most effective new therapies, via microbiome optimization, all to the benefit of patients and the physicians treating them.

Learn More

Our Mission

Together, we can diversify patient groups in clinical trials so all are included and given the best opportunity for good health and long-term well-being. Data collected from this study will be used to develop the most effective new therapies, via microbiome optimization, all to the benefit of patients and the physicians treating them.

Everyone can be a health hero! Be a representative in your community!

Enroll Now

How To Participate?

There's Power In Taking Control Of Your Health

Find a clinical site near you that participates in the Argonaut clinical observation of patients who are healthy, diseased or currently diagnosed with cancer.

We need to better understand the impact of gut microbiome composition! We can't do that without you!

Get Involved

Join the Gut-health Newsletter

A Partnership Aligned For A Cure

Persephone's mission is to unlock thge potential of the gut microbiome to develop equitable precision medicine.

Learn More

Curebase is powered by a software platform purpose-built for decentralized research.

Learn More

Accliante has a mission through the #NOWINCLUDED movement to grow a representative amount of minoirty participation in clinical trials.

Learn More